A clinical trial using engineered immune cells to hunt cancer cells has reported impressive results for solid tumours, a type ...

Our immune system is designed to protect us by recognizing and attacking infected or abnormal cells. However, cancer cells ...

CAR T-cell therapy uses your own immune cells to fight cancer in a new way. It changes immune cells called T cells so they target tumors directly. It’s been approved to treat certain types of ...

Transformative research introduces CAR-T cells that flourish in tumor environments, paving the way for unparalleled advancements in cancer immunotherapy. At EPFL's School of Engineering ...

After treatment with CAR-T cells—immune cells engineered to attack cancer—patients sometimes tell their doctors they feel like they have "brain fog," or forgetfulness and difficulty concentrating.

While CAR T cell therapy—a personalized form of cancer immunotherapy first successfully developed by Carl June, MD, and his team at Penn—has revolutionized treatment for many blood cancers ...

Chimeric antigen receptor (CAR) T cells targeting CD19 have transformed the treatment of B-cell cancers, but many patients do not have long-term remission. We designed an anti-CD19 enhanced ...

You can reach Angus on Signal at angus.08. To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on ...

For decades, immunologists have explored CAR-T cell therapy as an effective tool to fight blood cancer. Increasingly, CAR-T cells are being explored as a potential silver bullet for treating ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now discovered that CAR molecules can be transferred from the CAR-T cells ...

A total of 17 patients were enrolled and received MCARH109 therapy. The maximum tolerated dose was identified at 150×10 6 CAR T cells. At the 450×10 6 CAR T-cell dose, 1 patient had grade 4 ...