Chimeric antigen receptor (CAR) T cells have a tough job. Engineered with a receptor that recognizes molecules decorating the surface of cancer cells, CAR T cells find and kill malignancies. However, ...

Chimeric antigen receptor (CAR) T cell therapy is an immunotherapy. It uses a patient’s own immune system to fight certain blood cancers. Normal T cells can “hook” onto cancer cells and kill them, but ...

Treatment of B-cell Acute Lymphoblastic Leukaemia has improved thanks to CAR-T therapies, but relapse is still very common.

Chimeric antigen receptor T cells, better known as CAR T cells, are powerful immunotherapy agents derived from a cancer patient’s existing immune cells and engineered to fight their specific tumors.

As interest in immunotherapy grows, so does the need for better tools to engineer CAR T cells. Could advances in CRISPR technology be the solution? In the last decade, a new immunotherapy tool has ...

Chimeric antigen receptor (CAR)-T cells are genetically engineered immune cells that are used in therapies against several cancer types. The CAR molecules, which mediate the therapeutic effect of ...

New CAR-T cell therapy shows promise for hard-to-treat cancers Date: March 10, 2025 Source: University of Colorado Anschutz Medical Campus Summary: Researchers have successfully developed a ...

After injection, the CAR-T cells got to work, multiplying and seeking out the target B cells, including the pathogenic ones underlying the autoimmune conditions. This persisted for a few weeks ...

Oncologists are increasingly favoring CAR T-cell therapy’s early-line use in relapsed/refractory multiple myeloma despite ...

B-cell acute lymphoblastic leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most ...