In the past 5–10 years there has been a growing trend for substituting conventional 5-fluorouracil with the oral prodrug of 5-fluorouracil, capecitabine, in chemotherapy regimens. This regimen ...
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It is notable that capecitabine compliance was monitored by counting returned tablets, and capecitabine ... In the discussion of broadening use of an oral fluoropyrimidine prodrug, it is relevant ...
During the first cycle of capecitabine development, three concomitant drugs were found to affect 5-FU clearance. [5] Paracetamol and morphine increased 5-FU clearance by 26% and 41%, respectively ...
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