Trials of Capecitabine-based Two-drug Combinations. Platinum (cisplatin and oxaliplatin), taxanes (paclitaxel and docetaxel) and irinotecan are active agents used to treat gastric cancer.

This fact is especially pertinent in cancer therapy, where most cytotoxic agents have a steep dose–response curve for toxicity and, consequently, narrow therapeutic windows. Capecitabine (Xeloda ...

Shares of Puma Biotechnology PBYI have rallied 35.3% in the past six months against the industry’s decline of 9.2%. The ...

The FDA granted orphan drug designation to HLX22 for gastric cancer, advancing global phase 3 trials to improve first-line ...

Dr. Sara M. Tolaney discussed HER2-positive breast cancer, highlighting key trials, evolving treatment strategies, and the ...

The conversion from accelerated approval to traditional approval was supported by data from the phase 3 KEYNOTE-811 trial.

Metronomic capecitabine plus AI significantly improved PFS and OS in HR-positive, HER2-negative metastatic breast cancer compared to AI alone. The MECCA trial enrolled 263 patients, with balanced ...

The chemotherapy drugs 5-FU and capecitabine could harm or kill you ... Birth control pills are also used to reduce the risk of cancer and to treat many medical conditions. Dr. Francis Collins ...

Novel HER2 therapies show strong intracranial efficacy, enabling systemic treatment over local therapy for small, ...

In a clinical practice guideline issued by the American Society for Radiation Oncology and published online Feb. 27 in ...