With clinical trials results trickling in, “antiaging” drugs that clear away senescent cells are proving to be promising — ...

NYU scientists have discovered that cancer cells work together to withstand challenging conditions, revealing new ...

As our bodies grow, cells proliferate to form tissues, and cells frequently have to be repaired or replaced throughout life..

The Cancer Paradox in Whales Whales are among the largest animals on Earth, yet they rarely get cancer. This seems ...

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery and Interventional Science at University College London has systematically ...

Cellular senescence (CS) marks a crucial cell cycle halt triggered in proliferating cells under various stress conditions, manifesting across different ...

p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells - ...

In this study, researchers restored p53 function in colorectal cancer cells, which led to slower cellular growth, increased cellular aging (senescence), and greater sensitivity to radiation therapy.

A cancer drug developed ten years ago at UCSF can also put the brakes on one of prostate cancer's deadliest molecular tricks.

Colibactin is a genotixin – it damages DNA. These mice also experienced cell senescence, which can cause cancer development. The researchers found lowered levels of regulation of gut health in the ...