Scientists have sequenced the complete genome of a roundworm used extensively in biological research, opening a new pathway ...

The activation of UPR mt not only depends on the TGF-β Dauer signaling pathway and the ASI-RIM neuronal axis, but also relies on the neurotransmitter dopamine and is negatively regulated by GABA.

The details of the signaling pathways regulating the differentiation of the cells are well studied in C. elegans, but up to now there was no indication for the common origin of dauer larvae and ...

The relevance of DAF-2 to C. elegans physiology was initially based on its association with a stage of diapause arrest called "dauer." Entry into this developmental stage, characterized by ...

Researchers have found a way to extend the lifetime of the C. elegans worm by 500%. But thinking the result means that humans will live to 400 years old is missing the point.

These particular ligands promote the maturation of the C. elegans reproductive capacity and prevent the organism from going into the immature long-lived larval phase called dauer diapause.

Researchers have provided experimental proof of a pathway that controls aging, finding that quieting some mobile DNA sequences in roundworms led to a longer life. Not only does the discovery ...

The study, “Parallel Pathways for Serotonin Biosynthesis and Metabolism in C. elegans, ” challenges the existing knowledge of how serotonin is produced and what happens to the neurotransmitter ...

However, C. elegans can generally only wriggle around without moving very far, meaning that they cannot escape the poor conditions that triggered the dauer state in the first place.

Scientists have found a way to increase the lifespan of C. elegans worms fivefold, which would be equivalent to a human reaching the age of 400.

The work, done in the nematode worm C. elegans and detailed in Scientific Reports, an online open access journal from the publishers of Nature, reveals for the first time how different genes in ...