By comparison, restoration of DAF-2 or AGE-1 in muscle regulated metabolism but did not reverse the dauer stage or lifespan ... essential functions in C. elegans, and the metabolic and ...

Another advantage of using C. elegans is that these worms have a simple ... by an "insulin-like" growth factor. This signaling pathway is analogous to the mammalian insulin pathway.

Caenorhabditis elegans drp-1 and fis-2 Regulate Distinct Cell-Death Execution Pathways Downstream of ced-3 and Independent ... drp-1 are not required for apoptosis activation in C. elegans. However, ...

For many years, a major challenge for neuroscientists has been the identification of the proteins that are responsible for communication at synapses. Now, using a large-scale RNA interference ...

Zhou, Q.H., Li, H.M., and Xue, D. (2011). Elimination of Paternal mitochondria through the lysosomal degradation pathway in C. elegans. Cell Research 21, 1662-1669 ...