The work represents “the first endogenous pathway for biosynthesis of terminal-alkyne-containing amino acids,” says Peng Chen, a bioorthogonal-chemistry expert at Peking University.

In the context of sequential tail truncation, the BimC motif and adjacent C-terminal amino acids are particularly important for sliding force. In addition, moderate tail truncation increases midzone ...

This C-99 retains the transmembrane domain, which γ-secretase first cuts internally between amino acids 48 and 49, or 49 and 50 (so-called epsilon cleavage). This releases into the cytosol either of ...

Protein C-terminus binding Definition: Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is ...

Next, they added a terminal amino acid segment (with the sequence UGGU) to the P1c2 (P1c2 UGGU). According to mass spectrometry results, this increased the peptide bond formation ability by 4.2 ...

Next, they added a terminal amino acid segment (with the sequence UGGU) to the P1c2 (P1c2 UGGU). According to mass spectrometry results, this increased the peptide bond formation ability by 4.2 ...