Most cases of breast cancer happen because healthy cells become abnormal and start to grow out of control. But sometimes, the genes you inherit from your parents are the reason. Learn what a gene ...

Women with breast cancer who were also carriers of the BRCA1 or BRCA2 mutation and received textured breast implants as part of their reconstructive surgery after mastectomy were 16 times more ...

Specifically, two categories of mutations — germline mutations and somatic mutations — may increase an individual’s risk of developing breast cancer.

BRCA mutations are inextricably linked with breasts, but they can also lead to cancer in the pancreas, the prostate, and maybe more parts of the body.

Dr. Evan Yu presents the new evidence-based guideline on genetic testing for metastatic prostate cancer. He discusses who should receive germline and somatic testing with next-generation sequencing ...

Somatic HER2 mutations are a novel class of therapeutic targets across different cancer types. Treatment with the tyrosine kinase inhibitor (TKI) neratinib as a single agent continues to be ...

Certain genetic mutations can boost your risk of breast cancer. Here’s what experts say you need to know when making the decision to get tested.

Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM also contribute to ...

Inavolisib is showing promising results for patients with hormone receptor-positive, HER2-negative metastatic breast cancer that tests positive for a PIK3CA mutation ...

Researchers have pinpointed what could be the early genetic origins of breast cancer -- cancer-like mutations appearing in the cells of healthy women. In a new study, the international ...

CancerVar efficiently captures quality big somatic cancer mutation data and utilizes artificial intelligence (AI) tools to categorize them based on the somatic variant interpretation guidelines.

Women with breast cancer who were also carriers of the BRCA1 or BRCA2 mutation and received textured breast implants as part of their reconstructive surgery after mastectomy were 16 times more ...