This kills the bacteria. Some bacteria produce beta-lactamase, an enzyme that can damage penicillin and block its effects. To stop this from happening, penicillins may be combined with substances ...

Zaynich is based on cefepime, a well-established beta-lactam antibiotic, combined with a novel beta-lactamase inhibitor ...

Some bacteria can become resistant to penicillin by producing beta-lactamase, which is a bacterial enzyme that destroys the beta-lactam ring of penicillin and makes it ineffective. One common ...

Further analyses of the samples revealed that the variations in fungal response to antibiotic treatment was connected to the activity of the enzyme beta-lactamase, which is produced by endogenous ...

Among children treated with an oral agent, the recurrence rate was 16/42 (38.1%) following penicillin or amoxicillin and 10/36 (27.8%) following a beta-lactamase resistant agent (adjusted odds ...

Extended-spectrum beta-lactamases (ESBLs) are enzymes or chemicals produced by germs like certain bacteria. These enzymes make bacterial infections harder to treat with antibiotics. Here's what ...

These advancements contribute to the discovery of improved beta lactam antibiotics and beta lactamase inhibitors, addressing antimicrobial resistance and infectious diseases.

Dublin, April 03, 2023 (GLOBE NEWSWIRE) -- The "Global Antibiotics Market (2023-2028) by Action Mechanism, Drug Class, Spectrum, and Geography, Competitive Analysis, Impact of Covid-19 with Ansoff ...

We study known drug targets and also aim to discover new Achilles' heel opportunities: the main targets are proteins involved in peptidoglycan metabolism including penicillin-binding proteins (PBPs), ...