The active component of the wonder drug penicillin and related antibiotics such as the cephalosporins is an "enchanted ring," called the β-lactam ring ... strain on the bond angles that carbon ...

Their innovative approach employs nickel and hydrocarbon sources that are abundant on Earth to access value-added beta-lactam products ... that differ in the ring size from β-lactams.

sharing together a specific structural feature of the beta-lactam ring. Among them, penicillin is one of the earliest discovered and most widely used antibiotic agents. In addition, penicillin is ...