Antibiotics such as beta-lactams—penicillin ... titled “Demonstration of the role of cell wall homeostasis in Staphylococcus aureus growth and the action of bactericidal antibiotics.” ...

Penicillin belongs to the beta-lactam family ... In order to form the cell wall, a single peptidoglycan chain is cross-linked to other peptidoglycan chains through the action of the enzyme DD ...

The mechanism which allows beta-lactam antibiotics ... discovered that β-lactam antibiotics kill MRSA (Methicillin Resistant S. aureus) by creating holes in the cell wall which enlarge as ...

These antibiotics are characterized by a beta-lactam ring in the molecule’s center, and function by interfering with the synthesis of the bacterial cell wall ... method of action to aminoglycosides.

Thus, most bacteria possess both, a PG cell wall and FtsZ ... and also to produce beta-lactamases that could confer resistance against beta-lactam antibiotics. Figure 1: Radioactive labelling ...

Lilliam Ambroggio, PhD, MPH, of Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, and colleagues compared the effectiveness of beta-lactam monotherapy — recommended by Pediatric ...

The bactericidal action of vancomycin results primarily from inhibition of cell-wall biosynthesis. In addition, vancomycin alters bacterial-cell-membrane permeability and RNA synthesis.