Researchers have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity - a harmful condition linked to the progression of type 2 ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

She explained that human babies are born with a small amount of pancreatic “beta cells,” the only cells in the body that ...

The participants who ate mangoes experienced "significant" reductions in insulin resistance. Beta-cell function, the ability of the pancreas to produce and release insulin to manage normal glucose ...

If the mice received antibiotics during a 10-day window shortly after birth, they developed fewer beta cells—insulin-producing cells in the pancreas that regulate blood sugar. The antibiotic ...

If the mice received antibiotics during a 10-day window shortly after birth, they developed fewer beta cells -- insulin-producing cells in the pancreas that regulate blood sugar. The antibiotic ...

The new findings support icovamenib’s potential as a first-in-class, disease-modifying therapy by targeting beta-cell restoration, enhancing insulin secretion, and sustaining glycemic ...

The molecular glues in this case increase the binding between 14-3-3 proteins and ChREBPα, which is anchored in the cytoplasm of the beta cell by the 14-3-3 proteins. Under conditions of ...

If the mice received antibiotics during a 10-day window shortly after birth, they developed fewer beta cells—insulin-producing cells in the pancreas that regulate blood sugar. The antibiotic-treated ...