Metal-mediated base pairing in nucleic acids represents a transformative approach wherein traditional Watson–Crick hydrogen bonds are replaced or supplemented by coordinate bonds with metal ions. This ...

This article explores advanced oligonucleotide analysis techniques, including chromatography methods for therapeutic RNA, ...

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Despite being made from a relatively simple set of building blocks, ribonucleic acid (RNA) has a broad array of complex ...

Improve assay sensitivity and specificity with Locked Nucleic Acid oligonucleotides (LNA oligos) from LGC Biosearch Technologies. LNAs are RNA bases in which the ribose is “locked” with a methylene ...

The NIH Guidelines for Research Involving Recombinant or synthetic Nucleic Acid Molecules contain procedures for the containment of Recombinant or synthetic Nucleic Acid Molecules. Synthetic nucleic ...

Researchers at Harvard Medical School are studying the differences in human genomes to identify the genes underlying biological processes and human disease. One of the researchers, professor Steve ...