Understanding these fundamental processes holds great potential for developing new antibiotics that target these specific pathways in bacterial protein synthesis, according to the researchers.

In bacteria, this factor is called EF-P and ... this protein reacts to the metabolism of the cell and adapts protein ...

in addition to the approaches that are being pursued for the production of improved drugs that inhibit bacterial protein synthesis. Despite the large size of the ribosome, relatively few sites are ...

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy ...

PRIMARY isolates of chick embryo fibroblasts cultivated as monolayers were found to resume protein synthesis only after a delay of 24–48 hr. The extent of the lag period was dependent in part on ...

Another kind of antibiotic--tetracycline--also inhibits bacterial growth by stopping protein synthesis. Both bacteria and humans carry out protein synthesis on structures called ribosomes.

Antibiotics that inhibit protein synthesis are known to have some degree of antivirulence effects. Macrolides bind reversibly to 23S ribosomal RNA (rRNA) of the 50S subunit of bacterial ribosome ...

Cell-free protein synthesis (CFPS) eliminates the need to maintain living cells and allows greater control of reaction conditions than in vivo expression systems but is limited by its sensitivity ...

Understanding these fundamental processes holds great potential for developing new antibiotics that target these specific pathways in bacterial protein synthesis, according to the researchers.

This breakthrough involves the development of a novel antibiotic that shuts down bacterial protein synthesis. Called cresomycin (CRM), the antibiotic promises to tackle a wide array of drug-resistant ...

Understanding these fundamental processes holds great potential for developing new antibiotics that target these specific pathways in bacterial protein synthesis, according to the researchers.