testing positive for a germline BRCA1 variant. Germline BRCA 1 and BRCA 2 test results were available for all 450 men. These revealed 27 germline BRCA2 variants (6%), but only two germline BRCA1 ...

As a young breast cancer survivor with a BRCA1-positive diagnosis, I faced tough choices. Ultimately, I chose to undergo a laparoscopic prophylactic oophorectomy, a decision rooted in my ...

The former NBC news anchor, 49, revealed last month in an Instagram post that she had tested positive for the BRCA1 gene mutation, putting her at a higher risk for breast and ovarian cancer.

testing positive for a germline BRCA1 variant. Germline BRCA 1 and BRCA 2 test results were available for all 450 men. These revealed 27 germline BRCA2 variants (6%), but only 2 germline BRCA1 ...

Two sisters recently went viral on TikTok after publicly declaring their decision to get double mastectomies together. The decision came after learning of their family's long history with breast ...

BRCA mutations also raise your chances for ovarian ... Research suggests about only 10% to 20% of cases are HER2-positive. This means there’s a change in the HER2 gene that makes breast cells ...

BRCA-positive breast cancer after first-line chemotherapy. Helen Knight, director of medicines evaluation at NICE, said that the guidance “addresses a significant need by giving people with ...

[47,48] Although MRI is an effective surveillance modality in BRCA mutation carriers–especially in younger women–a significant proportion of women are still found to have node positive breast ...

That's a no brainer.'" She shared that genetic testing revealed she is positive for BRCA1. "I get the results back that I'm positive for BRCA1 which means my chances for getting breast cancer and ...

Olaparib is recommended, within its marketing authorisation, as an option for treating HER2-negative locally advanced or metastatic breast cancer with germline BRCA1 or BRCA2 mutations ... have ...

Olaparib (Lynparza, AstraZeneca) is indicated as 'monotherapy for the treatment of adult patients with germline BRCA1/2 mutations ... Patients with hormone receptor (HR) positive breast cancer should ...