Learn about the factors underlying autoimmune disease and current treatment strategies.

The odds are greater if you are a woman, you have a genetic predisposition to autoimmunity, or you are exposed to certain pollutants. These diseases include more than 100 lifelong and costly ...

When helpful species decline and potentially harmful ones flourish, this delicate balance tips toward autoimmunity. Research has found distinct microbiome signatures associated with various ...

Aly et al. [17] provided evidence that risk for islet autoimmunity drastically increased in DR3/4-DQ2/DQ8 siblings who shared both HLA haplotypes identical by descent with their diabetic proband ...

The common consensus for some time has been that the prevalence of autoimmunity and autoimmune diseases has been on the rise. Decidedly less common, however, is a widely accepted explanation of ...

In healthy mice in the absence of infection, this change did not trigger autoimmunity to the prostate. When the researchers infected mice with a bacterium that expressed the prostate self-peptide ...

Finally, the therapeutic effects have endured far beyond the initial treatment period and several have lost virtually all biomarkers of autoimmunity. Leonard H. Calabrese Of course, the usual cave ...

Immune dysregulation is often defined as an immune response that is directed against one of the body’s own tissues, cells or molecules (e.g. autoimmunity) or against an innocuous foreign molecule that ...

It also provides strong evidence that cross-reactivity between human and microbial proteins drives autoimmunity in at least two diseases and probably many others. Now that we understand the ...

Thyroid autoimmunity (TAI), infertility and miscarriage are currently issues of extreme interest that have attracted the attention of many investigators. Several papers have been published ...

Physicians should consider measuring anti-endothelial cell antibodies in patients with polycythemia vera, the investigators suggested. A new analysis of anti-endothelial cell antibodies (AECAs) in ...

In healthy mice in the absence of infection, this change did not trigger autoimmunity to the prostate. When the researchers infected mice with a bacterium that expressed the prostate self-peptide ...