Aurora kinases, a group of serine/threonine protein family, comprise Aurora A, B and C members and are involved in the regulation of cell division and mitosis. Aurora A overexpression correlates with ...

Proper activity of mitotic kinases is vital for error-free cell division. This work shows that during anaphase, Aurora A ...

The kinase activity of Aurora kinase A is required for preserving S-adenosylmethionine availability for histone methylation and epigenetic reprogramming during trained immunity induction in ...

Co announces the presentation of preclinical results for its Aurora kinase - angiogenesis inhibitor, ENMD-981693. In preclinical studies, ENMD-981693 has been shown to inhibit a unique profile of ...

“The results from the clinical trials of alisertib in small cell lung cancer suggest that the drug may represent a potentially promising treatment option for these patients and more specifically for ...

LONDON--(BUSINESS WIRE)--Ellipses Pharma Limited (“Ellipses”), a global drug development company focused on accelerating the development of new oncology treatments, has presented preliminary data from ...

Nurix Therapeutics, Inc. presented promising preclinical data at the AACR 2025 Annual Meeting, showcasing their innovative targeted protein degradation medicines aimed at addressing various cancers, ...

Mitotic kinase CDK1 phosphorylates LDHA at T18, reducing its incorporation into LDH tetramers and promoting formation of LDHB ...

A new study published in Science China Life Sciences shows that inhibition of Aurora kinases can promote the differentiation of liver cancer cells. The research was conducted by scientists from Peking ...