Once melanoma has spread to the brain ... identified focal adhesion kinase (FAK) as a potential target for new therapies. FAK is an enzyme that regulates cell growth, and, they found, is a major ...

The incidence of brain metastasis is high in patients with non ... EGF receptor (EGFR) tyrosine kinase inhibitors (TKIs), given their low molecular weight, may be able to reach a higher ...

“It's not that easy for cells to grow in the brain,” said Marsha Rosner, a cancer biologist at the University of Chicago. “They need some help.” Recent studies have shown that cancer cells secrete ...