SYD-101 contains a low dose of atropine sulfate, an antimuscarinic agent, in an ophthalmic solution. The NDA is supported by data from the phase 3 STAR trial (ClinicalTrials.gov Identifier: ...

noting that atropine -- a muscarinic receptor antagonist -- "is a well-established treatment for slowing myopia progression." ...

Homatropine is an anticholinergic that inhibits activity of the muscarinic acetylcholine receptor with less potency than atropine. Abuse potential (monitor). Life-threatening respiratory ...