Reasoning that astrocytes might have a role in synapse elimination ... Electrophysiological recordings revealed that each dLGN neuron received more synaptic inputs than usual.

Between the axon of a transmitting neuron and the dendrite of a receiving neuron is a gap called the synapse—the site at which signals are passed between the brain cells. The nervous system ...

Astrocytes are the major glial cell in the central nervous system. These polarized cells elaborate numerous processes that ensheath the vasculature and contact synapses. Astrocytes play important ...

A complete model of mitochondria function showing through simulations that Ca2+ uptake by mitochondria requires the activation of CB1Rs on both the astrocyte plasma membrane and the OMM at the same ...

iAssembloids combine hiPSC-derived neurons, microglia, and astrocytes in 3D spheres. CRISPRi screening revealed genes that affect neuron survival in iAssembloids but not in 2D monoculture. One gene, ...

The nucleus where the genes that modify neuron function are controlled is a long distance away from where neurons receive input from their synapses, which are located in distant dendrites that ...