Aromatase inhibitors like anastrozole and letrozole ... More research is needed to know the exact molecular mechanism of how PR modulate tumor growth and resistance to treatment.

RGT-419B is a potent CDK4 inhibitor with increased activity on CDK2 addressing a key mechanism of resistance ... in ...

This study reveals that Fe-doped boron nitride nanoparticles improve Anastrozole delivery, offering enhanced stability and targeted therapy for breast cancer.

Havah Therapeutics, a clinical stage biopharmaceutical company developing innovative therapies for prevention and treatment of breast cancers, announces the filing of a new provisional patent ...

Aromatase inhibitors (AIs) are becoming the hormonal treatment of choice for postmenopausal women with early breast cancer. Large, well-controlled clinical studies have established the efficacy ...

Aromatase inhibition could be an alternative to testosterone administration to mitigate declining androgen production in hypogonadal older men. Unlike testosterone replacement, aromatase ...

Considering taking supplements to treat aromatase inhibitor induced arthralgia? Below is a list of common natural remedies used to treat or reduce the symptoms of aromatase inhibitor induced ...

Early initiation of moderate-intensity aerobic exercise reduced pain compared with standard care among postmenopausal women who received aromatase inhibitors.

Aromatase inhibitors are able to block the biosynthesis of estrogen—a process that is essential in bone maturation, growth-plate fusion, and cessation of longitudinal growth. Aromatase ...

Cognitive dysfunction has been considered as a morbid condition that may possibly result from aromatase inhibitor therapy, the standard treatment in postmenopausal, estrogen/progesterone receptor ...