The exact therapeutic mechanism of action of antipsychotic drugs remains unclear. Recent evidence has shown that second-generation antipsychotic drugs (SGAs) are differentially associated with ...

Although several newer agents have recently gained approval, the mechanism of action of antipsychotics is still largely based on normalising dopaminergic neurotransmission which does not ...

Newly developed SGAs in addition to the benzamide antipsychotic drugs (sulpirides and amisulprides) and aripiprazole, appear to provide important advances in side effect profile and efficacy for ...

A new Northwestern Medicine study has identified the molecular mechanisms that cause a commonly prescribed antipsychotic drug to produce harmful side effects similar to Parkinson's disease ...

In this follow-up, I’ll take a look at two new antipsychotic medications—ulotaront and xanomeline/trospium—that seem to have genuinely novel mechanisms of action and try to answer whether ...

are drugs that target certain neurotransmitters to manage the symptoms of mental health conditions. Antipsychotics are classified into two groups depending on their “mechanism of action,” or ...

5 Blocking dopamine D 2 receptors may be a critical or even sufficient neuropharmacologic action of most clinically effective antipsychotic drugs, especially against hallucinations and delusions, but ...

Mechanisms of Q-Tc Interval Prolongation with Antidepressants and Antipsychotics Crumb and colleagues ... Though these drugs had little direct effect on cardiac ion channels, the effects that ...

Researchers at the Icahn School of Medicine at Mount Sinai have uncovered insights into the potential mechanism of action of the antipsychotic medication ... pave the way for the development of ...

Pregnant women on antipsychotic drugs can continue taking most of those ... So-called typical antipsychotics work by similar mechanisms to one another, but the second-generation atypical ...