Although bronchial hyperresponsiveness to cholinergic agents is a main feature of asthma, the role of anticholinergic drugs in chronic asthma management has been largely underestimated. Several ...

Possible alternate therapy for adults with poorly controlled asthma Date: September 20, 2010 Source: NIH/National Heart, Lung and Blood Institute ...

A recent clinical trial involving 210 asthma patients found that the anticholinergic drug tiotropium improved symptoms when added to a steroid inhaler, but the reason for this was unexplained.

The addition of multiple doses of inhaled ipratropium (an anticholinergic) to beta2-agonists may reduce the rate of hospital admissions in children and adults with moderate-to-severe asthma ...

Trelegy Ellipta combines fluticasone furoate, an inhaled corticosteroid with umeclidinium, an anticholinergic and vilanterol, a long-acting β2-adrenergic agonist.

A recent clinical trial involving 210 asthma patients found that the anticholinergic drug tiotropium improved symptoms when added to a steroid inhaler, but the reason for this was unexplained.

A drug commonly used for the treatment of chronic obstructive pulmonary disease (COPD) successfully treats adults whose asthma is not well-controlled on low doses of inhaled corticosteroids ...

Asthma is a chronic lung disease that inflames and narrows the airways. 1 Approximately 26 million people in the US currently have asthma. 2 Despite medical advances, more than half of patients ...

Kaiser Permanente Washington scientists report that higher cumulative anticholinergic exposure predicted a faster decline in ...

Long-acting Anticholinergic Drugs in Asthma . Tiotropium is the first long-acting anticholinergic drug that has been developed in the early 1990s and approved for the management of stable COPD.

The rate of admission was 14.2% in the anticholinergic group compared with 21.3% in the control group (P <0.0001, NNT 14, 95% CI 9-30). The NNT was 6 (95% CI 4-13) in trials that evaluated ...