The study, which presented a model of how bacteria balance peptidoglycan production and hydrolysis and shed new light on how antibiotics target the cell wall to kill bacteria, was published in an ...

For example, all antibiotics that target the cell wall – the thick protective layer surrounding bacterial cells – were grouped together and well separated from antibiotics that interfere with ...

The cell wall is essential for bacteria since it determines their shape and allows them to protect themselves, and many of our best antibiotics target the proteins that build and remodel this ...

To ensure that effective treatments for bacterial infections remain available in the future, antibiotics that target different ... two enzymes involved in cell wall and protein synthesis.

MraY is essential for the replication of bacteria and plays a role in the synthesis of the bacterial cell wall; it is also not a target of currently available commercial antibiotics.

The star of the story is saarvienin A, a brand-new glycopeptide antibiotic produced by an unusual strain of Amycolatopsis, a ...

Antibiotic effect on cell wall biosynthesis machinery inhibits cell division immediately The Bonn research team found that the formation of peptidoglycan is the driving force during the entire ...

Bacterial cell walls are primarily made of a unique ... This uniqueness makes it an important target for antibiotic development. Our immune system too looks for this signature to attack invading ...

An exception to this rule is penicillin-based antibiotics, where the target is in the cell wall itself. These antibiotics, known as carbapenems, were derived from penicillin some 48 years after it ...