Individual anthracycline dose Higher individual anthracycline doses are associated with increased late cardiotoxicity, even when cumulative doses are limited [54,60] Type of anthracycline ...

The study population consisted of 6,493 children with cancer who had received anthracycline chemotherapy on Pediatric Oncology Group (POG) protocols from 1974 to 1990. Cardiotoxicity, defined as ...

Unfortunately, life-threatening cardiotoxicity continues to compromise their usefulness. Despite more than four decades of investigation, the pathogenic mechanisms responsible for anthracycline ...

CHICAGO, IL—Taking sacubitril/valsartan (Entresto; Novartis) can help protect against the cardiotoxicity posed by anthracycline chemotherapy for high-risk patients with cancer, results from the ...

These results are in line with a previous study that also looked at using lisinopril or carvedilol and showed both could help improve cardiotoxicity-free survival among anthracycline-treated ...

but it did not take into account related cardiac risk factors or other classic risk factors of cardiotoxicity produced by anthracycline and trastuzumab (e.g., older age, concomitant chemotherapy ...

Anthracycline drugs are used to treat many ... One of the main concerns with anthracyclines is cardiotoxicity — damage to the heart muscle. The risk of a complication such as heart failure ...