Here, we developed individual-nucleotide resolution UV cross-linking and immunoprecipitation (iCLIP) to study the role of hnRNP C in splicing regulation. iCLIP data show that hnRNP C recognizes ...

Have students identify the two strands that make up DNA, the sugar-phosphate backbone, the individual nucleotide bases, and the nucleotide base pairs. To help students better understand the way ...

Human genomes vary quite a bit from individual to individual. These differences include single nucleotide changes, or "spelling mistakes" in the DNA sequence, but even more variation comes from ...

Until now, there has been no suitable way for scientists to explore the genetics of single tumor cells at a single-nucleotide resolution ... derived from a healthy individual (YH) who provided ...

the group analyzed the complete genome of a Japanese individual, the first time this has ever been done. Using a Bayesian decision method, the group identified over 3 million single nucleotide ...

So, rather than characterize these individual nucleotide changes in genes, Cheung and geneticist Richard Spielman employed microarray technology--essentially a genome chip that allows a researcher ...

Her findings suggest that the salvage pathway could be an access route for cancer cells to get their nucleotide supply when chemotherapeutic drugs inhibit the de novo pathway. But along the same lines ...

the group analyzed the complete genome of a Japanese individual, the first time this has ever been done. Using a Bayesian decision method, the group identified over 3 million single nucleotide ...