Particularly concerning are infections caused by highly resistant strains with ESBL and AmpC-producing Enterobacteriaceae (AmpC-E) and Carbapenemase-producing Enterobacterales (CPE), which are ...

However, resistance due to plasmid-mediated AmpC enzymes is less common than ESBL production in these organisms in most parts of the world. Since strains with AmpC genes are often MDR, ...

To become resistant, bacteria typically need to change particular genes like ampC in specific ways. To become tolerant, they just need to slow their growth, and there are many genes they could ...

Scientists at The University of Western Australia, in collaboration with researchers in Canada, have developed a new compound that can combat antibiotic-resistant bacteria. B-lactam antibiotics ...

Extended spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacteriaceae (AmpC-E), which are resistant to a number of commonly used antibiotics, have become a matter of great concern in both ...

Particularly important are infections caused by highly resistant strains with ESBL and AmpC-producing Enterobacteriaceae (AmpC-E), which are resistant to multiple antibiotics including penicillin ...

Extended spectrum beta-lactamase (ESBL) and AmpC-producing Enterobacteriaceae (AmpC-E), which are resistant to a number of commonly used antibiotics, have become a matter of great concern in both ...

There are several potential β-lactamase inhibitors under investigation, in different stages of preclinical and clinical trials. Although the results of Phase I and II studies were mostly not ...

The researchers also found that some of the horses in the Quebec study were passing E. coli carrying the ESBL/AmpC genes responsible for cephalosporin resistance, which is particularly worrisome.