Add-on therapy: may be used if not controlled on monotherapy; if dose-limiting adverse reactions with amlodipine 10mg, switch to 40/5mg tab. Replacement therapy: may be substituted for the ...
with optional dosage increases to amlodipine 10mg and candesartan cilexetil 16mg, respectively (in case of an insufficient treatment effect on the lower dose) after 6 weeks of treatment.