Each protein or peptide consists of a linear sequence of amino acids. The protein primary structure conventionally begins at the amino-terminal (N) end and continues until the carboxyl-terminal (C ...

Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal aspartic and glutamic acid residues in eukaryotic ...

The N terminus is defined as the beginning of the protein chain where the amino group of the first amino acid building block is available to react. Specifically targeting the N terminus is useful ...

Because of the height of the amino acid side chains, and also because the protofibrils tilt away from the fibril axis, each protofibril monomer contacts three monomers in the opposing protofilament.

The sequence and amino acid composition also affect the ... Most peptides of biological interest are derived from N-terminal, C-terminal, or internal sequences of native proteins.

The comparison of Atg2's amino acid sequence among different organisms revealed that N- and C-terminal regions [4] have been highly conserved. The group then prepared many Atg2 variants ...

They then further engineered the microbe to substitute the terminal alkyne amino acid for all the methionines in the microbe’s proteome. Chang plans to explore additional bioorthogonal chemistry ...

Amino acids are the building blocks that form polypeptides and ultimately proteins. Consequently, they are fundamental components of our bodies and vital for physiological functions such as protein ...