Progressive muscular atrophy (PMA) is clinically characterized solely by signs of lower motor neuron dysfunction, so patients with this condition are commonly excluded from ALS clinical trials.

AI-generated voice clones are bringing back the voices of people with MND, allowing some to communicate, connect, and even ...

A trial that will test a noninvasive device called MyoRegulator as a treatment for ALS was cleared to start enrolling ...

Patients do not typically transition to an upper motor neuron bladder or bowels Bladder and bowel anal-rectal sphincter remains flaccid, becomes highly complaint and is characterized by underactivity ...

Motor neurone disease (MND ... which is the most severe. ALS affects both the upper motor neurones that travel from the brain to the spinal cord and the lower motor neurones, which branch out ...

Multiple models have been proposed for the mechanism by which mutant superoxide dismutase 1 induces motor neuron death and amyotrophic lateral sclerosis ... of upper and lower motor neurons ...

there are different types of Motor Neuron Diseases which include; Amyotrophic lateral sclerosis (ALS) It was formerly known as Lou Gehrig's disease and can affect the upper and/or lower motor neurons.

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