The allele frequency spectrum in P ... using the program Bifurcator (Supplementary Methods). The root of each diagram is an allele, identified by an open square. The diagram is bidirectional ...

Ropeginterferon alfa-2b significantly reduces JAK2V617F variant allele frequency, achieving higher molecular response rates than hydroxyurea. Patients with higher molecular response experienced ...

accurately detects BRAF mutations in tumor biopsies and change in variant allele frequency (VAF) of BRAF mutation in ctDNA may be a surrogate marker for monitoring disease. The data is being ...

FORE Biotherapeutics Presents New Plixorafenib Results at AACR 2025 Demonstrating Pharmacodynamic Effect in Clinical Tumor Biopsies and Decreased V600E Mutant Allele Frequency in ctDNA of 85% of ...