Researchers used field data from 2012 to 2015 to study mortality and allele frequency changes in the sea star Pisaster ochraceus during a mass mortality event in north central California, and ...

In biological terms, evolution is a change in gene variant (a.k.a. “allele”) frequency in a population over time. It is not a force directing a species’ trajectory towards a certain goal.

Unraveling the genetic mechanisms behind adaptive evolution stands as a pivotal challenge in molecular biology. While ...

Objective Deep venous thrombosis (DVT), a potentially life-threatening condition with a high clinical incidence, represents a ...

Cell-Free Tumor DNA Dominant Clone Allele Frequency Is Associated With Poor Outcomes in Advanced Biliary Cancers Treated With Platinum-Based Chemotherapy. JCO Precis Oncol 6 , e2100274 (2022). DOI: 10 ...

FORE Biotherapeutics Presents New Plixorafenib Results at AACR 2025 Demonstrating Pharmacodynamic Effect in Clinical Tumor Biopsies and Decreased V600E Mutant Allele Frequency in ctDNA of 85% of ...

The variant allele frequency (VAF), or the number of mutant molecules over the total number of wild-type molecules at a specific genome location, was calculated from the ctDNA samples.