Azide–alkyne coupling in a nutshell. The 1,3-dipolar cycloaddition of azides and alkynes has become the model for click reactions. This cycloaddition has been known for over 100 years and was ...

New method for hydroboration of alkynes: Radicals induce unusual selectivity Date: August 30, 2018 Source: Kanazawa University Summary: A combination of organoboron and radical chemistry generates ...

Buttoned up biomolecules Click reaction for living systems: Bioorthogonal hydroamination of activated linear alkynes Peer-Reviewed Publication ...

Click chemistry is best known for a copper-catalyzed azide-alkyne reaction that makes it possible for certain chemical building blocks to "click" together in an irreversible linkage, analagous to ...

However, this reaction requires a toxic copper catalyst, making it unsuitable for living systems. An alternative is the use of cyclic alkynes, in which the triple bond is under so much strain that ...

A photocatalytic flow process activates simple gaseous alkanes for an atom economic late-stage alkylation of pharmaceutical ...

Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless share the Nobel Prize in Chemistry for discovering an easy way to “click” molecular building blocks together ...

Add one or two drops of 1% bromine in dichloromethane to one sample of each hydrocarbon. Compare the rate of the reactions and the conditions. Add one or two drops of 5% KMnO4 to the second sample of ...

Bowman and Stansbury received a grant along with ChBE alum Chris Kloxin for their proposed study, "CU-catalyzed azide-alkyne reactions for novel dental composite materials." Bowman's individual ...

Click chemistry is best known for a copper-catalyzed azide-alkyne reaction that makes it possible for certain chemical building blocks to "click" together in an irreversible linkage, analagous to ...