Medically reviewed by Brian H. Wetchler, DO The adrenal glands are two small glands located on top of the kidneys. They ...

Addison’s disease is a rare condition in which the adrenal glands do not produce enough of the hormones cortisol and ...

Potassium and renal function must be routinely assessed to minimize the risk of life-threatening hyperkalemia. This review discusses the role of aldosterone antagonists in the treatment of heart ...

Aldosterone antagonists (spironolactone ... New York Heart Association functional class IV symptoms, preserved renal function and a normal potassium concentration. Spironolactone was investigated ...

Aldosterone may induce perivascular and interstitial cardiac fibrosis that may reduce systolic function, increase cardiac stiffness, and thereby impair diastolic function, generating heterogeneous ...

Therefore, patients should be carefully selected for initiation of aldosterone antagonists. The guidelines recommend regular checks for serum potassium and levels and renal function at 1 week ...

The condition occurs when tiny benign nodules (abnormal tissue growths) in one or both adrenal glands produce excess aldosterone ... to control important bodily functions like blood pressure ...