Although obesity-induced reduction of adiponectin expression is primarily ascribed to a transcriptional regulation failure, the underlying mechanisms are largely undefined.

Adiponectin is a circulating hormone predominantly secreted from adipocytes. Unlike many other adipokines that are up-regulated in obesity, such as TNFα, IL-6, leptin and resistin, the ...

Researchers investigated the role between adiponectin and leptin in obesity-related carcinogenesis. Their findings suggest that the protein hormone adiponectin has potential for inhibiting the ...

Adiponectin, a hormone secreted by adipose tissue, plays a doubly important role in preserving pancreatic function: in lean people, it protects beta cells, which make insulin, and in obese people, it ...

While obesity is a well-known cause of cardiovascular disease, research from Sweden has now revealed that one of the body's obesity-related hormones -- adiponectin -- is also linked to ...

We examined the effect of varying degrees of obesity on the prevalence of the metabolic syndrome and its relation to insulin resistance and to C-reactive protein and adiponectin levels in a large ...

Researchers at the University of Toronto, Faculty of Medicine, Toronto, Canada, have discovered that adiponectin, a protein secreted from adipocytes, is a metabolic link that can explain, in part ...

Adiponectin, a hormone secreted by adipose tissue, plays a doubly important role in preserving pancreatic function: in lean people, it protects beta cells, which make insulin, and in obese people ...

Obesity, recognized as a complex and growing health issue, is associated with an increased risk of various cancers. A ...

It is apparent from these studies of obese and nonobese individuals that adiponectin levels are more tightly linked with insulin concentrations and insulin resistance than degree of obesity. Obese ...

A research team from Emory University School of Medicine investigated the role between adiponectin and leptin in obesity-related carcinogenesis. Their findings, published in the November issue of ...