Biopsy suggested pancreatic acinar cell cancer; serum lipase was elevated to 4 times normal. How to manage the patient?

However, they did show that injured pancreatic cells readily regenerate back into healthy acinar cells, which has implications for treating cancer and inflammation of the pancreas.

However, research on pancreatic acini has been significantly hampered due to the difficulty of culturing normal acinar cells in vitro. In this study, an in vitro model of the normal acinus, named ...

Microscopic image of the pancreas organoid. The magenta shows the cell nuclei, and the cyan highlights the acinar cells that secrete digestive enzymes. Researchers from the Organoid group ...

Researchers from the University of British Columbia (UBC) have uncovered a direct connection between high insulin ...

Acinar cells release enzymes that help break down food, while ductal cells form channels to carry the enzymes to the gut. Finally, endocrine cells produce hormones like insulin to control sugar ...

Acinar cells in the pancreas form new cell types to mitigate injury but are then susceptible to cancerous mutations.

image: Pancreatic acinar cells form a heterogeneous population of new cell types in response to injury with the potential to limit or drive disease. Acinar-derived clones labeled in red and green ...

When the transitioning cells returned to their original identity as acinar cells, the scientists found that some of the epigenetic marks on pancreatic cancer-linked genes remained for at least ...

Mice cells with permanently and selectively labeled pancreatic acinar cells (left panel, blue). At the same time, insulin-producing cells could be followed by a stain specific for insulin (middle ...