Many important antibiotics are becoming less effective against bacterial infections, as bacteria continue to evolve, gaining ...

coli with genetic drains that constantly burned ATP or its cousin nicotinamide adenine dinucleotide (NADH). Then, they pitted both the engineered strains and normal bacteria against ciprofloxacin. The ...

The drug and the genetic drains each slashed ATP, but rather than slowing down, the bacteria revved up. Respiration soared, and the cells spewed extra reactive-oxygen molecules that can damage DNA.

In the face of growing antibiotic resistance among bacterial infections, ... "Unlike BDQ and TBAJ-876, SQ31f binds a previously unknown site on ATP synthase," explains Rubinstein, ...

Doing so won't be easy, notes Shea, as bacteria have evolved multiple backups systems for this important class of transporters. "What's nice about this ATP-binding family is they all have an ATP ...

The researchers also discovered that in some cases, depleting ATP affects the phage’s control systems, causing it to breach the bacterial cell’s membrane too soon – before it has had a ...

A previously unknown protein in a family of bacteria found in soil and the human gut microbiome has been discovered – which could help drug delivery in cancer treatment. In a paper published in ...

Researchers have identified a previously unknown bacterial protein, the structure of which is being used in the design of protein nanoparticles for the targeted delivery of anticancer drugs to tumors.