AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress.

A recent study published in Life Metabolism reports that ROS, molecules often associated with oxidative stress, serve as ...

AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress. While upstream ...

A groundbreaking study led by researchers at the Masonic Medical Research Institute (MMRI) has identified a promising ...

Researchers demonstrated that systemic factors from young mice can rejuvenate the aging retina by alleviating cellular senescence and restoring function.

A groundbreaking new study led by researchers at the Masonic Medical Research Institute (MMRI) has identified a promising ...

AMPK signaling may have a critical role in aging-associated brain diseases. Some in vitro studies have shown that 1,5-anhydro-D-fructose (1,5-AF) induces AMPK activation.

This novel signaling axis highlights the complex interplay between the deacetylation and phosphorylation of AMPK in response to glucose and nutrient-sensing signals. Given AMPK’s well-established role ...

"This dual regulatory mechanism, defined by JNK and AMPK signaling and reinforced by the selective recruitment of DNMT3A and DOT1L, offers insights into how macrophages regulate lysosomal ...