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Research reveals a molecule that may help slow aging while on a restricted diet
That led them to conduct a second study to learn more about how LCA activates AMPK. They found that activation was dependent on signaling from certain members of the enzyme family called sirtuins.
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SOX9 Overexpression Ameliorates Metabolic Dysfunction-associated Steatohepatitis Through Activation of the AMPK Pathway (IMAGE)
Our findings demonstrate that SOX9 overexpression alleviates hepatic lipid accumulation in MASH by activating the AMPK pathway. These results highlight SOX9 as a promising therapeutic target for ...