High ADH levels mean that the aquaporins release the water back into the blood. When water is released back into the blood, plasma osmolality drops, leading to the blood becoming diluted.

ADH acts on the kidneys to increase water permeability in the collecting duct and distal convoluted tubule. Specifically, ADH acts on transmembrane protein channels called aquaporins that open up ...

Antidiuretic hormone (ADH) is responsible for regulating the body’s fluid balance. Doctors can use an ADH test to help diagnose underlying conditions that cause fluid and electrolyte imbalances ...