A bacterium makes a molecule that kills drug-resistant fungi in an unusual way — by targeting various phospholipid molecules in membranes. Read the paper: A polyene macrolide targeting ...

Phospholipid-binding domains vary widely in their degree of ligand specificity. Some are highly target specific, whereas others will bind to any acidic phospholipid. Target-specific domains ...

Changing a molecule's handedness is no simple feat ... PLD3 and PLD4 synthesize S,S-BMP, a key phospholipid enabling lipid degradation in lysosomes, Cell (2024). DOI: 10.1016/j.cell.

Many individual lipids, such as the serum cholesterol, phospholipid and various beta-lipoprotein fractions, have been extensively evaluated as indicators of coronary heart disease. Attempts have ...