If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally segregated, leading to genetic ...

If DNA bridges remain between chromosomes after cell division, chromosomes become improperly segregated, resulting in genetic ...

Abstract Faithful chromosome segregation requires the removal of all DNA bridges physically linking chromatids before the completion of cell division ...

Scientists have elucidated the molecular mechanism by which LEM-3 cuts DNA bridges during cytokinesis ... LEM-3 is a nuclease, and nucleases act like a surgical knife on DNA.

and IBS Research Fellow Stephane ROLLAND announced that they have elucidated the molecular mechanism by which LEM-3 cuts DNA bridges during cytokinesis. Cell division is an essential biological ...