RNA bundled in lipid nanoparticles trains T cells in mice to eliminate cancer. Coupled with noninvasive imaging, researchers ...

Amor Vegas' lab is now investigating whether CAR T cells let mice live not only healthier but also longer. If so, society will be one mouse step closer to the coveted fountain of youth.

Regulatory T-cell therapy calms autoimmune response from gluten-sensitive T cells in mice By Darren Incorvaia Mar 20, 2025 7:16am ...

Finally, to assess long-term toxicity, the researchers followed mice that received CARD11-PIK3R3 T cell therapies, including those that were part of the dose-response study, for up to 418 days.

MAIT cells are a subset of T lymphocytes that respond to microbial metabolites, the authors noted. “MAIT cells are found in humans, mice, and many other mammals.” ...

Mice normally live about two years, and research found the uPAR-targeting CAR T cells persisted and expanded for more than 15 months in mice as they grew from youth into older age. “In some ways, ...

This finding from their study carried out in mice, overturns traditional thinking that regulatory T cells exist as multiple specialist populations that are restricted to specific parts of the body.

This didn’t satisfy Masopust, so his team took cells from the immunized mice’s spleens and lymph nodes, expanded the cell populations in test tubes, injected about 100,000 into new mice, and ...

A CAR was initially developed with mouse IL-5 as the antigen-binding moiety. T-cells expressing this IL-5 CAR, which were eventually referred to as 5T cells, were found to effectively deplete IL-5 ...