In the first game No. 16 St. Francis (PA) will square off with No. 16 Alabama State, with a trip to Kentucky to take on the top overall seed Auburn on the line. In the second game, No. 11 North Carolina — a surprising inclusion in the tournament — takes on No.

In fact, the Ivy League has had a winning team in the NCAA Tournament in back-to-back years. With Yale playing in its second straight March Madness, can the Bulldogs pull off another first-round upset in the 2025 NCAA Tournament bracket?

Madness teams could pull off upsets in the first round? Here's eight bracket-buster predictions for Round of 64 NCAA Tournament bracket.