L'Épine is a commune in the Marne department in the Grand Est region of north-eastern France. It is located 8 km east of Châlons-en-Champa…L'Épine is a commune in the Marne department in the Grand Est region of north-eastern France. It is located 8 km east of Châlons-en-Champagne and about 45 km south-east of Reims, on the route nationale N3.