Toledo is a city in Lucas County, Ohio, United States, and its county seat. It is located at the western end of Lake Erie along the Maumee River…Toledo is a city in Lucas County, Ohio, United States, and its county seat. It is located at the western end of Lake Erie along the Maumee River. Toledo is the fourth-most populous city in Ohio and 86th-most populous city in the United States, with a population of 270,871 at the 2020 census. The Toledo metropolitan area had 606,240 residents in 2020. Toledo also serves as a major trade center for the Midwest; its port is the fifth-busiest on the Great Lakes.